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Anafranil 50mg single capsule
  • Brand:Anafranil Generic
  • Composition:CLOMIPRAMINE
 
 

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  • Descriptions

    Anafranil [Clomipramine] is a tricyclic antidepressant, widely used in the treatment of Obsessive Compulsive Disorder [OCD]. It is also used to treat Major Depression, Panic Disorder, and Narcolepsy.

    Clomipramine corrects the chemical imbalance caused when the neurotransmitters - Serotonin, Norepinephrine, and Dopamine - get reattached to the parent nerve. Generic Clomipramine is considered to be an extremely powerful serotonin reuptake inhibitor, besides being a norepinephrine and dopamine reuptake inhibitor, possessing antiadrenergic, antihistamine and anticholinergic properties.
  • Uses of Generic Anafranil 50mg

    Obsessive Compulsive Disorder [OCD] occurs when people are driven by their thoughts, feelings, or ideas to the extent that this becomes an obsession with them, compelling them to perform certain actions.

    Clomipramine is the earliest medicine being used in the treatment of OCD. It is not recommended for those who are below 18, unless the psychiatrist considers this medicine to be essential for the child.

    It is also used to treat Enuresis in children and adolescents, chronic pain associated with "tension" headaches, and premature ejaculation.
  • How to use Generic Clomipramine

    The medicine must be taken exactly as prescribed, for it is individualized, dependant on medical history and condition. The age factor is another consideration - children and adolescents, if treated with Anafranil, are given a lower dose than adults.

    Initially, low doses are prescribed twice or thrice daily. The dose can be gradually increased, as the body adjusts to the medicine, and eventually only a single dose is given prior to bedtime.

    The medicine can be taken with food to avoid a stomach upset.
  • Side effects

    Less serious side effects commonly associated with this medicine can include:-
    • Constipation, or conversely Diarrhea;

    • Nausea, which may lead to Vomiting;

    • Weight gain, or loss;

    • Change in libido.

    An allergic reaction will show up as - Rash, Hives, Itching, or a Swelling in the face/tongue/throat.

    Talk to your doctor immediately if you have an allergic reaction, or should any symptom become worse or bothersome, or should you have any unusual or serious side effect, such as:-
    • Suicidal ideation;

    • Irregular heartbeat;

    • Confusion;

    • Fever with profuse perspiration;

    • Loss of bladder control, or difficulty in urinating;

    • Severe fatigue;

    • Tingling, numbness, or pain in the hands or feet;

    • Jaundice;

    • Drowsiness.
  • Clomipramine Interactions

    Some of the following drugs/substances are amongst those with which this medicine interacts:-
    • Anti-seizure medicines such as Phenytoin, or Phenobarbital;

    • Anticoagulants such as Warfarin;

    • Antipsychotic medicines like Haloperidol;

    • Antihypertensive medicines like Clonidine, or Guanethidine;

    • Oral contraceptives;

    • Histamine antagonists like Cimetidine to treat GERD;

    • Medications for certain heart problems such as Digoxin, Flecainide, Propafenone, or Quinidine;

    • Benztropine for treating Parkinson's disease and akathisia;

    • Barbiturates like Secobarbital for insomnia & some kinds of epilepsy;

    • Medicines to treat irritable Bowel syndrome like Dicyclomine;

    • Disulfiram [for chronic alcoholism];

    • Certain OTC medicines [including herbal products] to treat cold and sleep disorders;

    • CNS stimulants like Alcohol, Caffeine, Nicotine, or "Street" drugs.
  • Overdose

    If you suspect an overdose, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Overdose symptoms can include seizures, coma, loss of coordination, rapid heartbeat, labored breathing, blue discoloration of the skin, stiffness of muscles, drowsiness, or restlessness.
  • Precautions

    • Let your treating doctor know your complete medical history, making a special mention of any heart, liver or kidney disease, seizures, brain damage, glaucoma, hyperthyroidism, pre-existing bone marrow depression, any problem related to the blood pressure, a urinary or prostate problem, or if you are being treated with ECT.

    • Inform the psychiatrist if anyone in your family has had Bipolar Disorder, suicidal ideation or attempted to commit suicide.

    • Give a complete list of the medicines [including over-the-counter and prescription]-nutritional supplements-herbal products you are taking, for some of them may interact with this medicine, and any specific allergies, particularly to anything in Anafranil.

    • Do not combine "street" drugs or alcohol with this medicine.

    • When you take this medicine, it may increase suicidal ideation at the beginning of the therapy, or whenever the dose is increased/decreased - keep your doctor informed.

    • It can take several weeks for you to feel better when you begin to take this drug. However, you must continue to take this medicine, even when you feel well.

    • Don’t suddenly stop taking the medicine, or you may have withdrawal symptoms bringing about dizziness, fever, nausea, vomiting, headache, irritability, or problems with sleeping.

    • Before you go for any surgery - including dental procedures - let the surgeon/dentist know that you are taking this medication.

    • Pregnant, or lactating women, as well as those planning to have a child must consult their doctor before beginning this therapy.

    • Elderly people must be careful about their movements as this medicine can make them drowsy.

    • It is recommended that people do not drive, swim, climb, or perform other activities that involve fully alert mental faculties, while taking this medicine.
  • Missed Dose

    The missed dose can be taken if there is plenty of time left for the next dose, otherwise skip the missed dose and follow your normal dosing schedule. Don't double your dose.
  • Contraindication

    This medicine is contraindicated if taken in certain conditions or with certain substances:-
    • MAOIs such as Phenelzine, Selegiline, Linezolid, or Tranylcypromine;

    • SSRIs like Fluoxetine, Sertraline, or Paroxetine;

    • Other antidepressants;

    • Narcotic medications.
  • Storage

    When you purchase Anafranil, store it in its' container, properly capped, protecting it from excessive heat, light and dampness.

    Keep this Medicine away from Children and Pets.
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