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The anti-viral drug, Tamiflu, is used to control influenza, in adults and children who are above 1 year. It is made up of Oseltamivir that prevents influenza from spreading in the body.

The Influenza viruses A, B and C are similarly structured. Hemagglutinin and Neuraminidase are large glycoproteins on the outer side of the viral particles. Tamiflu generic is effective against Influenza A and B, and functions as an inhibitor of the neuraminidase protein; it works on the infected cells, preventing the virus from growing and spreading further.

The H1N1 virus - responsible for the flu pandemic in 2009 - was an Influenza Virus A, which is associated with causing the most severe kind of influenza. Spread by wild aquatic birds, it is conveyed to other animals, domestic poultry, and human beings. Influenza B is less common than Influenza A, and affects human beings much more than other species. Some immunity to Influenza B is acquired at an early age.

Oseltamivir, an anti-viral, possesses properties that enable it to control the spread of different strains of viruses in our body. People who develop high fever, headaches, feel extremely tired, have body aches, watery eyes, a cough, or sore throat maybe combined with nasal congestion, can all be treated with Tamiflu in the influenza season. In children, even diarrhea may be present.

It comes in two forms - capsules and suspension. It can be taken regardless of food, but if that upsets your stomach, you can take it with food or milk. If you have difficulty in swallowing the capsule, you can carefully empty the entire contents of the capsule into a small bowl, mix it thoroughly into some sweetened liquid, and then consume it right away. But whether you are taking the capsule, or the suspension, take the dose as prescribed by your doctor.

When Tamiflu is used to treat influenza, it is normally taken twice a day [morning and evening] for 5 days.

When Tamiflu is used as a preventive against influenza, it is generally taken once a day for 10 days at a stretch, but if there is a flu outbreak, then it can be taken once a day for 6 weeks.

The side effects associated with Oseltamivir include:-
Nausea, maybe even Vomiting, Headache, Stomachache, Diarrhea.

Contact your doctor at once, if you experience any allergic reaction such as: Rash, Hives, Itching, Blisters, Swelling of the tongue or face.

Seek emergency medical help if any symptom persists or bothers you, and especially if you experience the following serious side effects:-

• Labored or fast breathing;


• Change in skin color - bluish-gray [in children];


• Insufficient intake of fluids [in children];


• Not waking up or refusing to interact [in children];


• Nightmares, or hallucinations [in children and adolescents especially];


• When small children get so irritable that they refuse to be held;


• Persistent and/or severe vomiting;


• Symptoms of flu first improve but return with fever and cough;


• Pain and/or pressure in the chest/abdomen;


• Confused thinking;


• Suddenly feeling dizzy;


• High fever that lasts more than 3 days.

Tamiflu can interact with some medicines, including:-

• Immunosuppressants like Imuran, Ciclosporin, Sirolimus, or Protopic Topical;


• Antimetabolites such as Methotrexate;


• Medications taken for chemotherapy in cancer;


• Oral steroids like Dexamethasone;


• Corticosteroids which also suppress the immune system such as Prednisone;


• Adrenocortical steroids such as Methylprednisolone.

If you feel you have overdosed on this medicine, or any symptom is becoming bothersome, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222.

While you may take Tamiflu, you may still be able to pass on the flu to others. In order to prevent this, you must wash your hands often, and do not share cups and utensils with others so that the virus does not spread.

Increasing liquid intake, warm showers, warm compresses, nasal strips and humidifiers can help to reduce body aches and nasal congestion.

Try to take as much rest as you can, until you feel better.

As influenza spreads through coughing or sneezing, avoid touching your eyes, nose or mouth. Disinfect household surfaces or anything you touch [tabletops, telephones, other things] with a diluted chlorine bleach solution.

When there is a flu outbreak, avoid large gatherings.

Do not share your medicine with others even if they have the same symptoms as you, for it can harm them.

Try not to miss a dose, as that may not cure your infection and leave you susceptible to the flu. If you miss a dose of this medicine, and remember it when just 2 hours are left for your next dose, then leave the missed dose and follow your regular schedule. If you miss more than one dose, speak to your doctor. Never double doses.

Before taking Tamiflu, you must give your complete medical history to the doctor, especially mentioning if you suffer from any autoimmune disease like rheumatoid arthritis, systemic lupus erythematosus, HIV, AIDS, or any disease of the heart, lungs, liver, or kidneys.

Let the doctor know about all the medications [prescription and OTC]-nutritional supplements-herbal products you are taking, and whether you have any allergies to anything, especially to Oseltamavir, so that the doctor can curtail the use of certain medicines, and prescribe the correct dose regimen for you.

Women who are pregnant, lactating, or plan to have a child, must inform the doctor of their condition, before taking Tamiflu.

Let your treating doctor know if you have fructose intolerance - a condition in which the body is unable to break down fruit sugar [sorbitol] - as Tamiflu suspension contains sorbitol.

Intake of Oseltamivir may cause some people to have hallucinations, nightmares, or they may try to harm themselves. Though this has happened more in children and teenagers, adults also have experienced these symptoms. If a child is being treated with this medicine, then parents have to be alert and watch for these signs.

Tamiflu has not replaced the yearly flu vaccine. If you have taken or plan to take the intranasal flu vaccine, let your doctor know about this, as Oseltamivir can reduce the effectiveness of the flu vaccine if it is taken 48 hours before or 2 weeks after the flu vaccine.

If your flu symptoms remain with you after your course of Oseltamivir is over, contact your doctor.

The capsules should be kept in their container at room temperature, away from heat and dampness, while the suspension can be kept in the refrigerator [don't freeze]. Discard the unused suspension after 10 days, and any medication that is outdated or no longer required; for safe disposal methods, you can take the help of your pharmacist.

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