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  • Brand:Plavix Generic
  • Composition:CLOPIDOGREL
 
 
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  • Plavix [Clopidogrel bisulfate] Description

    This medicine, Plavix [Clopidogrel bisulphate] 75mg prevents the formation of blot clots in specific heart or blood vessel conditions. It prevents a heart attack or stroke in individuals who have a pre-existing condition, and also helps those with peripheral arterial disease from developing a heart attack, or a stroke. Clopidogrel prevents blood clotting by disallowing platelets in the bloodstream from sticking to each other, and averts heart attack or stroke.
  • Uses of Generic Clopidogrel

    Clopidogrel, considered to be the best-selling medicine for preventing the formation of blood clots, reduces the risk of cardiovascular death, MI [new or re-infarction, fatal or non-fatal], stroke, refractory ischemia, and helps people suffering from peripheral arterial disease who have poor circulation of blood in their legs. It is administered to patients who have undergone angioplasty and received stents for re-opening their clogged arteries.
  • Missed Dose

    A single dose is not likely to be missed. If your cardiologist has told you to take more than one dose a day, and you miss a dose, try to take it if there is sufficient time for the next one, otherwise follow your normal schedule, but don't double your dose.
  • Side-effects

    Some of the less serious and common side effects may include:-

    • Easy bruising;

    • Minor bleeding;

    • Mild headache;

    • Mild dizziness;

    • Stomachache, maybe with diarrhea;

    • Constipation.


    If you have an allergic reaction such as:- itching, rash, swelling in the mouth/face/lips/tongue, tightness in the chest, or difficulty in breathing, stop the medicine and ask your doctor for help. If any symptom persists or gets worse, or if any other serious or unusual symptoms occur such as the following, contact the physician and seek emergency help immediately:

    • Coughing up blood, or dark vomit;

    • Black, or tarry stools;

    • Urine problems - urinating more/less, or passing dark urine;

    • Bleeding in the eye, or difficulty in seeing properly;

    • Unusual/severe bleeding due to cuts;

    • Bleeding from the nose/gums;

    • Increased menstrual bleeding, or unexplained vaginal bleeding;

    • Chest pain, with/without pain spreading across the shoulder/arm;

    • Perspiring;

    • Sudden numbness/weakness, especially if only one side of the body is affected;

    • Malaise;

    • Jaundice;

    • Slurred speech;

    • Unsteady gait;

    • Fever, with/without persisting sore throat;

    • Feeling disoriented.

  • Overdose

    Plavix overdose symptoms may include: shortness of breath, feeling completely exhausted, or blood in the vomit/stools, for which emergency medical attention should be sought at once. US residents can call the US national poison hotline at 1-800-222-1222.
  • Interactions

    Some of the medicines with which it interacts, include:-

    • Injectable drugs to prevent blood-clots like Alteplase [TPA];

    • Medicines for the heart such as Fluvastatin, or Zocor;

    • Anticoagulants such as Coumadin, or Ticlopidine;

    • NSAIDs like Ibuprofen, Toradol, or Indomethacin;

    • Protease Inhibitors like Etravirine for treating HIV;

    • Anti-cancer medications such as Nolvadex;

    • SSRI antidepressants like Fluoxetine, or Fluvoxamine;

    • Anti-diabetic medications such as Tolbutamide;

    • Anti-seizure medications like Felbamate, or Phenytoin;

    • Anti-fungals Fluconazole, Ketoconazole, or Voriconazole;

    • Histamine antagonists for the treatment of gastric ulcers and to prevent GI bleeding such as Cimetidine;

    • Proton Pump Inhibitors like Esomeprazole, or Omeprazole;

    • Water-pills such as Furosemide, or Torsemide.

  • Storage & Contraindication

    When you buy Plavix, keep it at room temperature, safe from heat, light and dampness; storing it out of reach of children and pets.

    Contraindication


    This medicine is contraindicated in those who have:-

    • An allergy to anything in Plavix;

    • Bleeding gastric ulcers;

    • Intracranial hemorrhage.

  • Precautions


    • Before treatment begins, patients [or their parents] must inform the doctor/pediatrician about all the ailments yo've suffered from, particularly if you have any disease of the heart/liver/kidney, a history of stroke, hemophilia [bleeding/clotting disorder], ulcerative colitis, if you have undergone a recent surgery, or if you have active bleeding from a stomach ulcer/brain injury.

    • Let the doctor know about all medicines [OTC and prescription]-nutritional supplements-herbal products you are taking, and any allergies you have, particularly to anything in Plavix.

    • Plavix should be discontinued 5 days prior to any surgery; so should you require even a dental procedure, inform the surgeon/dentist that you are taking this medicine.

    • As Plavix stops the blood from clotting, it increases the risk of bleeding even if it is a minor injury, so if you have any bleeding that does not stop, contact your doctor at once.

    • It is recommended that you avoid activities, including sports that could lead to easy bruising or bleeding, while exercising greater care as you shave, or brush your teeth.

    • After you purchase Plavix and begin this therapy, you must keep all your lab appointments, as the cardiologist will be monitoring your blood levels to rule out side effects.

    • Those who drive or operate machinery will have to be careful when taking this therapy, as it can cause drowsiness.

    • Daily consumption of alcohol, along with this medication, can increase the risk of stomach bleeding, so you should reduce your intake of alcohol/alcoholic beverages.

    • Pregnant or lactating women, as well as those who are planning to conceive, must consult their doctor before taking this medicine.

  • Dosage of Plavix Tablets

    Generally, Plavix has to be taken once daily and can be taken with a glass of water, with or without food. Take the medicine exactly as prescribed, at the same time every day.
  • Notes

    Read the Patient Information every time you buy a refill - it may have some new information. Your cardiologist will be able to tell you more about the uses, side effects, interactions, and precautions associated with this medication.
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