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Azathioprine, an immunosuppressive agent used to prevent rejection after a kidney transplant.

It may also be used to treat rheumatoid arthritis and other conditions as determined by your doctor.

Take exactly as prescribed by your health care professional.

Contact your paediatrician regarding the use of this medicine in children.

Check with your doctor if any of these most common side effects persist or become bothersome, mild nausea or vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; itching; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue);
chest pain or tightness;
dark urine;
dizziness;
fever, chills, or sore throat;
increased or painful urination;
muscle pain or aches;
pale or fatty stools;
severe or persistent nausea, vomiting, or diarrhea;
shortness of breath;
stomach pain;
unusual bleeding or bruising;
unusual growths or lumps;
unusual weakness or fatigue;
yellowing of the eyes or skin

Tell your health care provider if you are taking any other medicines, especially any of the following:

mercaptopurine
hydantoins
azathioprine
anticoagulants
angiotensin-converting enzyme (ace) inhibitors
aminosalicylates
allopurinol
alkylating agents

This may not be a complete list of all interactions that may occur. Ask your health care provider if Azathioprine may interact with other medicines that you take.

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.

Lab tests, including complete blood counts, liver function, and TPMT enzyme activity, may be performed while you use Azathioprine.

If you conceive whilst on a course with this medication inform your doctor immediately.

If you need to undergo any kind of surgery, inform your doctor you are taking this medicine.

Inform your doctor if you are pregnant, breast feeding or planning to conceive.

Avoid alcohol and alcohol containing beverages whilst on a course with this medication.

Do not treat yourself with OTC medication whilst on a course with this medication, without consulting with your health care professional.

Do not have any vaccinations without your prescribers’ approval.

Do not double doses to make up for a missed dose. Consult your health care professional about your missed dose.

Ask your doctor or pharmacist for more information.

STORE THIS MEDICINE at room temperature, away from heat and light.

Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you have kidney or liver problems, or gout

if you have an infection, a history of frequent or prolonged infections, or you have recently had a vaccination

if you have a history of bone marrow problems, anaemia, low white blood cell or platelet levels, or unusual bruising or bleeding

if you have certain enzyme deficiencies (thiopurine methyltransferase [TPMT] or xanthine oxidase)

if you have recently had a blood transfusion

if you are taking a disease-modifying antirheumatic drug (DMARD) (eg, methotrexate, adalimumab)